chanelink logo
CHANELINK
English

New machine learning algorithm accurately decodes molecular optical 'fingerprints'

1344
2025-05-09 10:57:00
See translation

Recently, a research team from Rice University in the United States developed a new machine learning algorithm - Peak Sensitive Elastic Network Logistic Regression (PSE-LR). This algorithm is adept at interpreting the unique optical characteristics of molecules, materials, and disease biomarkers, which can help achieve faster and more accurate medical diagnosis and sample analysis. The relevant paper was published in the latest issue of the journal Nano.

The research team stated that the core breakthrough of this technology lies in teaching computers to recognize unique "fingerprints" generated by the interaction between molecules or materials and light. With the help of this technology, in the future, doctors may be able to capture early signals of Alzheimer's disease by simply shining light on a drop of liquid or tissue sample.

PSE-LR not only has the ability to distinguish autumn hair, but also has the interpretability of being open and honest. Unlike other "black box" machine learning models, it can generate clear "feature importance maps" that accurately highlight key spectral segments, making diagnostic results reliable, interpretable, traceable, and easy to verify.

Compared with other machine learning models, PSE-LR shows superior performance, especially in identifying subtle or overlapping spectral features. In addition, in the subsequent series of validation experiments, the performance of the algorithm was also commendable, including the successful detection of the trace presence of COVID-19 spike protein in the liquid, the accurate identification of neuroprotective components in mouse brain tissue, the effective differentiation of microscopic spectral differences in Alzheimer's disease samples, and the identification of the unique optical characteristics of two-dimensional semiconductor materials.

Source: Opticsky

Related Recommendations

  • Osram's new laser headlights "Yutianba" are unveiled

    Recently, OSRAM, a well-known global automotive lighting brand, announced the launch of its modified new laser headlights - the Yutianba laser headlights. Laser headlights were once regarded by many car companies as the "successor" of LED headlights, and German century old automotive lighting expert Osram is precisely the pioneer of laser light sources for automotive headlights. Since the 2014 BMW...

    2024-05-06
    See translation

  • Photonics leaders call for EU to implement € 2 billion plan

    Photonics21 has released a new position paper urging the European Commission to create a € 2 billion ($2.35 billion) independent plan for photonics in the 2028-2034 budget, and warning that Europe must 'invest in light, otherwise it will fall into darkness'.Channelled through the European Union’s Multiannual Financial Framework (MFF), the funding is designed to unlock a further €6–8 billion from i...

    10-14
    See translation

  • The use of laser equipment to recover refractory materials can reduce 800,000 tons of carbon dioxide emissions

    Refractory material can withstand high temperature above 1500℃. They are essential materials for industrial furnaces that produce glass or ceramics, non-ferrous metals and steel. The service life of manufactured refractory products can range from a few days to many years, depending on the material, the temperature in the melting vessel and other operating parameters. As a result, although ...

    2023-09-04
    See translation

  • Overview of Residual Stress in Metal Additive Manufacturing: Detection Techniques, Numerical Simulation, and Mitigation Strategies

    Researchers from Shantou University have reported a review of residual stresses in metal additive manufacturing: detection techniques, numerical simulations, and mitigation strategies. The relevant paper titled "A comprehensive review of residual stress in metal additive manufacturing: detection techniques, numerical simulations, and mitigation strategies" was published in the Journal of the Brazi...

    2024-12-20
    See translation

  • Sweden's powerful laser system generates ultra short laser pulses

    For the first time, researchers at Umeå University, Sweden, have demonstrated the full capabilities of their large-scale laser facility. The team reports generating a combination of ultrashort laser pulses, extreme peak power, and precisely controlled waveforms that make it possible to explore the fastest processes in nature.Umeå’s laser is 11 m long and generates very short pulses László Vei...

    08-20
    See translation