chanelink logo
CHANELINK
English

New machine learning algorithm accurately decodes molecular optical 'fingerprints'

1470
2025-05-09 10:57:00
See translation

Recently, a research team from Rice University in the United States developed a new machine learning algorithm - Peak Sensitive Elastic Network Logistic Regression (PSE-LR). This algorithm is adept at interpreting the unique optical characteristics of molecules, materials, and disease biomarkers, which can help achieve faster and more accurate medical diagnosis and sample analysis. The relevant paper was published in the latest issue of the journal Nano.

The research team stated that the core breakthrough of this technology lies in teaching computers to recognize unique "fingerprints" generated by the interaction between molecules or materials and light. With the help of this technology, in the future, doctors may be able to capture early signals of Alzheimer's disease by simply shining light on a drop of liquid or tissue sample.

PSE-LR not only has the ability to distinguish autumn hair, but also has the interpretability of being open and honest. Unlike other "black box" machine learning models, it can generate clear "feature importance maps" that accurately highlight key spectral segments, making diagnostic results reliable, interpretable, traceable, and easy to verify.

Compared with other machine learning models, PSE-LR shows superior performance, especially in identifying subtle or overlapping spectral features. In addition, in the subsequent series of validation experiments, the performance of the algorithm was also commendable, including the successful detection of the trace presence of COVID-19 spike protein in the liquid, the accurate identification of neuroprotective components in mouse brain tissue, the effective differentiation of microscopic spectral differences in Alzheimer's disease samples, and the identification of the unique optical characteristics of two-dimensional semiconductor materials.

Source: Opticsky

Related Recommendations

  • TriLite has partnered with AMS OSram to develop AR smart glasses displays

    TriLite has announced a technical collaboration with ams OSRAM, a global leader in smart sensors and transmitters. Ams Osram will supply its sub-assembled RGB laser diode to "light up" TriLite's Trixel® 3 laser beam scanner (LBS), the world's smallest AR smart glasses projection display.The award-winning Trixel® 3 LBS offers breakthrough compactness and light weight, as well as a bright an...

    2023-09-06
    See translation

  • The rare decay of the Higgs boson may point to physics beyond the standard model

    Particle physicists have detected for the first time a new decay of the Higgs boson, revealing subtle differences predicted by the standard model and potentially pointing to new physics beyond it. The research results are published in the journal Physical Review Letters.The theoretically predicted Higgs boson since the 1960s was finally discovered in the European CERN laboratory in 2012. As a quan...

    2024-01-26
    See translation

  • Shanghai Institute of Optics and Fine Mechanics has made progress in composite material based picosecond mirrors

    Recently, the High Power Laser Element Technology and Engineering Department of the Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, has made progress in the research of composite based picosecond mirrors. The related research results were published in Optics and Laser Technology under the title of "Hybrid Material Based Mirror Coatings for Picosed Laser Applications"....

    2024-07-12
    See translation

  • Xi'an Institute of Optics and Fine Mechanics has made new progress in the field of metasurface nonlinear photonics

    Recently, the Research Group of Nonlinear Photonics Technology and Applications in the State Key Laboratory of Transient Optics and Photonics Technology of Xi'an Institute of Optics and Fine Mechanics has made important progress in the field of super surface nonlinear photonics. Relevant research results were published in the internationally famous journal Nanoscale Horizons. The first author of t...

    2024-09-27
    See translation

  • Scientists use the light inside fibers as thin as hair to calculate

    Scientists from Heriot Watt University in Edinburgh, Scotland have discovered a powerful new method for programming optical circuits, which is crucial for the delivery of future technologies such as unbreakable communication networks and ultrafast quantum computers."Light can carry a large amount of information, and optical circuits that use light instead of electricity are seen as the next majo...

    2024-01-20
    See translation