chanelink logo
CHANELINK
简体中文

New machine learning algorithm accurately decodes molecular optical 'fingerprints'

1303
2025-05-09 10:57:00
查看翻译

Recently, a research team from Rice University in the United States developed a new machine learning algorithm - Peak Sensitive Elastic Network Logistic Regression (PSE-LR). This algorithm is adept at interpreting the unique optical characteristics of molecules, materials, and disease biomarkers, which can help achieve faster and more accurate medical diagnosis and sample analysis. The relevant paper was published in the latest issue of the journal Nano.

The research team stated that the core breakthrough of this technology lies in teaching computers to recognize unique "fingerprints" generated by the interaction between molecules or materials and light. With the help of this technology, in the future, doctors may be able to capture early signals of Alzheimer's disease by simply shining light on a drop of liquid or tissue sample.

PSE-LR not only has the ability to distinguish autumn hair, but also has the interpretability of being open and honest. Unlike other "black box" machine learning models, it can generate clear "feature importance maps" that accurately highlight key spectral segments, making diagnostic results reliable, interpretable, traceable, and easy to verify.

Compared with other machine learning models, PSE-LR shows superior performance, especially in identifying subtle or overlapping spectral features. In addition, in the subsequent series of validation experiments, the performance of the algorithm was also commendable, including the successful detection of the trace presence of COVID-19 spike protein in the liquid, the accurate identification of neuroprotective components in mouse brain tissue, the effective differentiation of microscopic spectral differences in Alzheimer's disease samples, and the identification of the unique optical characteristics of two-dimensional semiconductor materials.

Source: Opticsky

相关推荐

  • The role of PTFE in laser processing

    Polytetrafluoroethylene (PTFE) has improved the efficiency and repeatability of nanosecond and picosecond laser processing technologies used in microelectronics and display glass manufacturing. In the field of precision manufacturing, the demand for efficient and repeatable processes is crucial. The laser structure of glass and laser ablation of silicon substrates are key areas where precision p...

    2024-07-26
    查看翻译

  • New insights into the interaction between femtosecond laser and living tissue

    The N-linear optical microscope has completely changed our ability to observe and understand complex biological processes. However, light can also harm organisms. However, little is known about the mechanisms behind the irreversible disturbances of strong light on cellular processes.To address this gap, the research teams of Hanieh Fattahi and Daniel Wehner from the Max Planck Institute for Photos...

    2024-06-07
    查看翻译

  • Mazak will push economical laser cutting processing equipment to Europe

    Recently, Yamazaki Mazak, a well-known Japanese machine tool manufacturer, announced that it will unveil its economic laser processing star Optiplex 3015 Ez for the first time in the European market at the upcoming 2024 EuroBLECH exhibition. This carefully crafted laser processing machine not only combines high-quality processing capabilities with affordable prices, but also aims to open the doo...

    2024-09-25
    查看翻译

  • The Welding Application of Fiber Laser in the Food and Beverage Industry

    As is well known, food and beverage product manufacturers have strict requirements in ensuring the hygiene and cleanliness of their equipment. Once these devices and components are designed or manufactured improperly, they are likely to cause pollution, ultimately leading to health hazards, brand reputation damage, and expensive recall actions. The shortage of labor and raw materials further exace...

    2023-10-19
    查看翻译

  • Reverse Modeling of 3D Scanning Reading in Hong Kong: Production Innovation in the Digital Era

    In the wave of the digital age, Hong Kong, as an international business center, constantly explores the application of new technologies in the manufacturing industry. Among them, 3D scanning and reverse modeling technology is emerging, bringing a new production innovation to the manufacturing industry. This article will explore the application of 3D scanning and reverse modeling in Hong Kong, as w...

    2024-03-30
    查看翻译