chanelink logo
CHANELINK
Tiếng Việt

New machine learning algorithm accurately decodes molecular optical 'fingerprints'

636
2025-05-09 10:57:00
Xem bản dịch

Recently, a research team from Rice University in the United States developed a new machine learning algorithm - Peak Sensitive Elastic Network Logistic Regression (PSE-LR). This algorithm is adept at interpreting the unique optical characteristics of molecules, materials, and disease biomarkers, which can help achieve faster and more accurate medical diagnosis and sample analysis. The relevant paper was published in the latest issue of the journal Nano.

The research team stated that the core breakthrough of this technology lies in teaching computers to recognize unique "fingerprints" generated by the interaction between molecules or materials and light. With the help of this technology, in the future, doctors may be able to capture early signals of Alzheimer's disease by simply shining light on a drop of liquid or tissue sample.

PSE-LR not only has the ability to distinguish autumn hair, but also has the interpretability of being open and honest. Unlike other "black box" machine learning models, it can generate clear "feature importance maps" that accurately highlight key spectral segments, making diagnostic results reliable, interpretable, traceable, and easy to verify.

Compared with other machine learning models, PSE-LR shows superior performance, especially in identifying subtle or overlapping spectral features. In addition, in the subsequent series of validation experiments, the performance of the algorithm was also commendable, including the successful detection of the trace presence of COVID-19 spike protein in the liquid, the accurate identification of neuroprotective components in mouse brain tissue, the effective differentiation of microscopic spectral differences in Alzheimer's disease samples, and the identification of the unique optical characteristics of two-dimensional semiconductor materials.

Source: Opticsky

Đề xuất liên quan

  • China University of Science and Technology has made significant progress in the field of pure red perovskite light-emitting diodes

    Recently, four research groups from the University of Science and Technology of China, namely Yao Hongbin, Fan Fengjia, Lin Yue, and Hu Wei, have collaborated to make significant progress in the field of pure red perovskite light-emitting diodes (LEDs). The team independently invented the Electrical Excitation Transient Spectroscopy (EETA) technology and used it to reveal that hole leakage is the ...

    05-12
    Xem bản dịch

  • Shanghai Optical Machinery Institute has made progress in laser assisted connection of metal carbon fiber composite heterojunction materials

    Recently, the research team of Yang Shanglu from the Laser Intelligent Manufacturing Technology R&D Center of the Chinese Academy of Sciences Shanghai Institute of Optics and Fine Mechanics has made new progress in the laser assisted connection of metal carbon fiber composite heterostructure joints.The team used an adjustable flat top rectangular semiconductor laser as a heat source to achieve...

    2023-09-01
    Xem bản dịch

  • The use of laser equipment to recover refractory materials can reduce 800,000 tons of carbon dioxide emissions

    Refractory material can withstand high temperature above 1500℃. They are essential materials for industrial furnaces that produce glass or ceramics, non-ferrous metals and steel. The service life of manufactured refractory products can range from a few days to many years, depending on the material, the temperature in the melting vessel and other operating parameters. As a result, although ...

    2023-09-04
    Xem bản dịch

  • Edmund Optics acquisition son－x

    Recently, globally renowned optical component manufacturer Edmund Optics announced that the company has acquired ultrasonic assisted systems and high-precision optical manufacturer son-x.Edmund Optics, as a leader in optical technology solutions, has been serving various fields such as life sciences, biomedicine, industrial testing, semiconductors, and laser processing since its establishment in 1...

    01-22
    Xem bản dịch

  • Innovative nanoparticle analysis: achieving breakthrough 3D imaging using X-ray lasers

    The latest progress in X-ray laser technology has opened up a new era of nanoscale exploration, bringing unprecedented opportunities for materials science and nanotechnology. Researchers have developed a novel imaging technique that can directly visualize separated nanosamples in free flight, capturing their complex structures with stunning details. This breakthrough method relies on single cohere...

    2024-03-05
    Xem bản dịch