chanelink logo
CHANELINK
Русский

New machine learning algorithm accurately decodes molecular optical 'fingerprints'

1304
2025-05-09 10:57:00
Посмотреть перевод

Recently, a research team from Rice University in the United States developed a new machine learning algorithm - Peak Sensitive Elastic Network Logistic Regression (PSE-LR). This algorithm is adept at interpreting the unique optical characteristics of molecules, materials, and disease biomarkers, which can help achieve faster and more accurate medical diagnosis and sample analysis. The relevant paper was published in the latest issue of the journal Nano.

The research team stated that the core breakthrough of this technology lies in teaching computers to recognize unique "fingerprints" generated by the interaction between molecules or materials and light. With the help of this technology, in the future, doctors may be able to capture early signals of Alzheimer's disease by simply shining light on a drop of liquid or tissue sample.

PSE-LR not only has the ability to distinguish autumn hair, but also has the interpretability of being open and honest. Unlike other "black box" machine learning models, it can generate clear "feature importance maps" that accurately highlight key spectral segments, making diagnostic results reliable, interpretable, traceable, and easy to verify.

Compared with other machine learning models, PSE-LR shows superior performance, especially in identifying subtle or overlapping spectral features. In addition, in the subsequent series of validation experiments, the performance of the algorithm was also commendable, including the successful detection of the trace presence of COVID-19 spike protein in the liquid, the accurate identification of neuroprotective components in mouse brain tissue, the effective differentiation of microscopic spectral differences in Alzheimer's disease samples, and the identification of the unique optical characteristics of two-dimensional semiconductor materials.

Source: Opticsky

Связанные рекомендации

  • Enlightra and DESY Hamburg developed an improved and scalable comb laser

    Laser technology startup Enlightra collaborates with DESY Hamburg to develop and design more stable and efficient comb lasers. This work demonstrates a microresonator with programmable synthetic reflection, providing tailored injection feedback for driving lasers. This technology has significantly improved compared to traditional self injection locking technology and can be produced using standard...

    2024-01-26
    Посмотреть перевод

  • Laser communication is expected to completely change optical links

    Laser technology is becoming a game changer in the field of satellite communication (SATCOM), capable of creating ultra secure networks that can transmit large amounts of data at unprecedented speeds through satellite networks and constellations.With continuous progress, the industry is ready for growth and collaboration, seizing the untapped potential of disconnected populations. The ability to h...

    2023-09-20
    Посмотреть перевод

  • An optical display technology based on mechanical optical mechanism

    The optical properties of afterglow luminescent particles in mechanical quenching and mechanical luminescence have aroused great interest in various technological applications. However, for specific photon applications, clearer explanations are needed for these unusual events.Recently, scientists from Pohang University of Science and Technology have designed an optical display technology with ALP ...

    2024-03-12
    Посмотреть перевод

  • Emerson launches a new type of laser welding machine that can efficiently and flexibly process medical precision components

    Recently, Emerson, the global leader in industrial automation, launched the all-new Branson ™ The GLX-1 laser welding machine, with its outstanding flexibility and innovative technology, accurately meets the urgent market demand for connecting small, complex or delicate plastic components. Its compact volume and modular design make it easy to integrate into the ISO-8 cleanroom environment, while t...

    2024-06-04
    Посмотреть перевод

  • Probe organization of photoacoustic devices using low-cost laser diodes

    Photoacoustic technology provides a non-invasive method for detecting biological tissues, but its clinical application is limited, partly due to the large volume and high cost of laser sources. A compact PA sensing instrument powered by laser diodes for biomedical tissue diagnosis can provide clinical doctors with a practical and effective tool for evaluating breast diseases.By providing a cost-ef...

    2024-03-06
    Посмотреть перевод