chanelink logo
CHANELINK
日本語

New machine learning algorithm accurately decodes molecular optical 'fingerprints'

363
2025-05-09 10:57:00
翻訳を見る

Recently, a research team from Rice University in the United States developed a new machine learning algorithm - Peak Sensitive Elastic Network Logistic Regression (PSE-LR). This algorithm is adept at interpreting the unique optical characteristics of molecules, materials, and disease biomarkers, which can help achieve faster and more accurate medical diagnosis and sample analysis. The relevant paper was published in the latest issue of the journal Nano.

The research team stated that the core breakthrough of this technology lies in teaching computers to recognize unique "fingerprints" generated by the interaction between molecules or materials and light. With the help of this technology, in the future, doctors may be able to capture early signals of Alzheimer's disease by simply shining light on a drop of liquid or tissue sample.

PSE-LR not only has the ability to distinguish autumn hair, but also has the interpretability of being open and honest. Unlike other "black box" machine learning models, it can generate clear "feature importance maps" that accurately highlight key spectral segments, making diagnostic results reliable, interpretable, traceable, and easy to verify.

Compared with other machine learning models, PSE-LR shows superior performance, especially in identifying subtle or overlapping spectral features. In addition, in the subsequent series of validation experiments, the performance of the algorithm was also commendable, including the successful detection of the trace presence of COVID-19 spike protein in the liquid, the accurate identification of neuroprotective components in mouse brain tissue, the effective differentiation of microscopic spectral differences in Alzheimer's disease samples, and the identification of the unique optical characteristics of two-dimensional semiconductor materials.

Source: Opticsky

関連のおすすめ

  • Monport enhances K40 laser cutting machine through air assisted technology

    Monport Laser has launched its latest breakthrough innovative product, the Monport 40W Pro CO2 laser engraving machine, with air assistance. This cutting-edge machine has set a new standard for precision carving, providing excellent performance and a series of upgraded functions. The Monport 40W Pro surpasses its predecessor, the Monport 40W Laser, in all aspects, making it a game-changing solutio...

    2023-10-11
    翻訳を見る

  • Artists transform paper into meticulous laser cutting designs

    In the past few years, paper artists have demonstrated the versatility of their common fiber materials. Some people manually cut or carve paper, while others combine traditional craftsmanship with digital design. Ibbini Studio is in this situation. Abu Dhabi artist Julia Ibni collaborated with computer scientist Stephen Noye to create sculptural paper works inspired by decorative patterns such as ...

    2024-01-23
    翻訳を見る

  • Implementing and studying non Hermitian topological physics using mode-locked lasers

    A mode-locked laser is an advanced laser that can generate very short optical pulses with durations ranging from femtoseconds to picoseconds. These lasers are widely used for studying ultrafast and nonlinear optical phenomena, but they have also been proven to be applicable to various technological applications.Researchers at the California Institute of Technology have recently been exploring the ...

    2024-03-27
    翻訳を見る

  • The market accounts for up to 70%! Meere is continuously expanding its market layout

    According to Korean media reports, Meere, a semiconductor and display equipment manufacturer from South Korea, is continuously expanding its presence in the high stack semiconductor market, including its HBM business.In fact, Meere itself is the world's top manufacturer of display edge grinding mechanisms, with a market share of up to 70%. It is based on its accumulation of display microfabricatio...

    2024-06-25
    翻訳を見る

  • Making Infrared Light Visible: New Equipment Utilizes 2D Materials to Convert Infrared Light

    Infrared imaging and sensing technology can be used in various fields, from astronomy to chemistry. For example, when infrared light passes through a gas, sensing changes in light can help scientists identify specific properties of the gas. The use of visible light may not always achieve this sensing.However, existing infrared sensors are bulky and inefficient. In addition, due to the use of infra...

    2024-06-24
    翻訳を見る