Ελληνικά

New insights into the interaction between femtosecond laser and living tissue

725

2024-06-07 14:10:38

Δείτε τη μετάφραση

The N-linear optical microscope has completely changed our ability to observe and understand complex biological processes. However, light can also harm organisms. However, little is known about the mechanisms behind the irreversible disturbances of strong light on cellular processes.

To address this gap, the research teams of Hanieh Fattahi and Daniel Wehner from the Max Planck Institute for Photoscience (MPL), as well as Max Planck Zentrum f ü r Physik und Medizin, collaborated to determine the conditions under which strong pulsed lasers can be used in the body without damaging the organism.

The international team based in Erlangen used vertebrate zebrafish to investigate the mechanism of deep tissue light damage triggered by femtosecond excitation pulses at the cellular level. The research results have been published in the Journal of Communication Physics.

The first author of this publication, Dr. Soyeon Jun from the MPL "Femtosecond Field Mirror" group led by Fattahi, explained, "We have demonstrated that when the central nervous system (CNS) of zebrafish is irradiated with 1030 nm femtosecond pulses, it suddenly occurs at the extreme peak intensity required for low-density plasma formation.".

As long as the peak intensity is below the low plasma density threshold, this allows for non-invasive increase in imaging residence time and photon flux during 1030 nm irradiation. This is crucial for nonlinear unlabeled microscopes.

"These findings have greatly promoted the advancement of deep tissue imaging technology and innovative microscopy techniques, such as femtosecond field microscopy, which is currently being developed in my group. This technology can capture high spatial resolution, unlabeled images with attosecond time resolution," Fattahi said.

"Our research findings not only highlight the value of collaboration in the fields of physics and biology, but also pave the way for in vivo applications to achieve precise manipulation of the central nervous system based on light," added Wehner, head of the Neuroregeneration Research Group.

Source: Laser Net

Σχετικές προτάσεις

A new approach to 3D printing has been published in a Nature journal

In the last century, the improvement of mechanical properties of structural metals was mainly achieved through the creation of increasingly complex chemical compositions. The complexity of this ingredient increases costs, creates supply fragility, and makes recycling more complex.As a relatively new metal processing technology, metal 3D printing provides the possibility to re-examine and simplify ...

2024-11-29
Δείτε τη μετάφραση
Researchers have discovered new multiphoton effects in quantum interference of light

An international research team from Leibniz University in Hanover and Strathclyde University in Glasgow overturned the previous hypothesis about the influence of multiphoton components in the thermal field and the interference effect of parameterized single photons. The journal Physical Review Letters published the team's research."We have demonstrated through experiments that the interference eff...

2024-01-24
Δείτε τη μετάφραση
Changchun Institute of Optics and Fine Mechanics has developed a high brightness HiBBEE non-uniform waveguide semiconductor laser

High brightness semiconductor lasers have extremely important applications in fields such as laser radar. Traditional semiconductor lasers face challenges such as large vertical divergence angle, elliptical beam output, multiple lateral modes, and poor beam quality, which limit the direct application of high brightness semiconductor lasers.In response to this challenge, the team from the Bimberg S...

03-18
Δείτε τη μετάφραση
New method doubles and accelerates thermal tuning of optical chips, supporting two current and voltage regulation methods

Silicon based quantum chip technology is one of the hot research directions in the field of integrated photonics. Thanks to compatibility with CMOS technology and silicon material characteristics, silicon-based integrated optical chips and devices have many advantages such as low cost, small size, low power consumption, and high integration, providing an ideal platform for large-scale optical comp...

2024-04-02
Δείτε τη μετάφραση
Professor Wu Dong's team at the University of Science and Technology of China created a "dancing microrobot" using femtosecond laser composite materials.

It was learned from the University of Science and Technology of China that the team of Professor Wu Dong of the Micro and Nano Engineering Laboratory of the school proposed a femtosecond laser two-in-one multi-material processing strategy, manufactured a micromechanical joint composed of temperature-sensitive hydrogel and metal nanoparticles, and then developed a multi-joint humanoid micromachine ...

2023-08-11
Δείτε τη μετάφραση

New insights into the interaction between femtosecond laser and living tissue

A new approach to 3D printing has been published in a Nature journal

Researchers have discovered new multiphoton effects in quantum interference of light

Changchun Institute of Optics and Fine Mechanics has developed a high brightness HiBBEE non-uniform waveguide semiconductor laser

New method doubles and accelerates thermal tuning of optical chips, supporting two current and voltage regulation methods

Professor Wu Dong's team at the University of Science and Technology of China created a "dancing microrobot" using femtosecond laser composite materials.